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欧盟评估扩展使用非转基因阿达青霉菌株AE-HP生产的α-L-鼠李糖苷酶的安全性

放大字体  缩小字体 发布日期:2024-07-02  来源:   作者:泽夕  浏览次数:67
核心提示:2024年7月1日,欧盟食品安全局就一种食品酶α-L-鼠李糖苷酶(α-l-rhamnosidase)的安全性评价发布意见。
     2024年7月1日,欧盟食品安全局就一种食品酶α-L-鼠李糖苷酶(α-l-rhamnosidase)的安全性评价发布意见。
 
  据了解,这种食品酶是由非转基因阿达青霉菌株AE-HP生产的,旨在用于四种食品生产过程。
 
  经过评估,专家小组得出结论,这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下:
 
  The food enzyme α-l-rhamnosidase (α-l-rhamnoside rhamnohydrolase; EC 3.2.1.40) is produced with Penicillium adametzii strain AE-HP by Amano Enzymes Inc. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that this food enzyme did not give rise to safety concerns when used in two food manufacturing processes. Subsequently, the applicant has requested to extend its use to include two additional processes. In this assessment, EFSA updated the safety evaluation of this food enzyme when used in a total of four food manufacturing processes. Dietary exposure to the food enzyme–total organic solids (TOS) was calculated to be up to 0.022 mg TOS/kg body weight (bw) per day in European populations. Using the no observed adverse effect level reported in the previous opinion (300 mg TOS/kg bw per day, the highest dose tested), the Panel derived a margin of exposure of at least 13,636. based on the data provided for the previous evaluation and the revised margin of exposure in the present evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the revised intended conditions of use.
 
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